Nuclear microscopy for biological tissue research at GNS

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Kennedy, J.V.; Markwitz, A. 2003 Nuclear microscopy for biological tissue research at GNS . Lower Hutt: Institute of Geological & Nuclear Sciences. Institute of Geological & Nuclear Sciences science report 2003/16 17 p.


Abstract: For the first time at GNS, nuclear microscopy studies on biomedical samples are developed. It uses the upgraded microprobe beam line for rat tissue analysis, which is a world-wide growing area of IBA. This pilot project is used to probe for heavy metals in biological tissue specimens to reveal information on elemental distribution in cells at intercellular level. We have demonstrated this study into rat heart tissue samples, where the coronary risk factors, the link between heart disease and stored heavy metals like Fe and Cu has been the subject of growing attention in the recent years. The details of the technique, sample preparation and preliminary results are discussed. (auth)